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别名 CD84 molecule
Anti-CD84 Antibody (4H83) 是一种 Rabbit 抗体,靶向 CD84。Anti-CD84 Antibody (4H83) 可用于 ELISA,ELISA(Cap)。
Anti-CD84 Antibody (4H83) 是一种 Rabbit 抗体,靶向 CD84。Anti-CD84 Antibody (4H83) 可用于 ELISA,ELISA(Cap)。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μL | ¥ 780 | 5日内发货 | |
| 100 μL | ¥ 2,289 | 5日内发货 |
| 产品描述 | Anti-CD84 Antibody (4H83) is a Rabbit antibody targeting CD84. Anti-CD84 Antibody (4H83) can be used in ELISA,ELISA(Cap). |
| 别名 | CD84 molecule |
| Ig Type | Rabbit IgG |
| 克隆号 | 4H83 |
| 反应种属 | Human |
| 特异性 | Human CD84 |
| 应用 | ELISAELISA(Cap) |
| 推荐剂量 | ELISA: 1:5000-1:10000; ELISA(Cap): 1:250-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD84 (rh CD84; TMPY-00715; NP_003865.1; Met1-Gly225). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | The CD2 family receptors are type I transmembrane glycoproteins belonging to immunoglobulin (Ig) superfamily characterized by a membrane-proximal Ig constant 2 (C2) domain and a membrane-distal variable (V) domain that is responsible for ligand recognition. CD84, also known as LY9B and SLAMF5, is a homophilic member of the SLAM (signaling lymphocyte activation molecule) subfamily of the CD2 family. The SLAM family receptorsmediate signal transduction through the interaction of its ITSM (immunoreceptor tyrosine-based switch motifs) in the intracellular region and the SH2 domain of adaptor molecules SAP (SLAM-associated protein) and EAT-2 (EWS-activated transcript 2), and accordingly modulate both adaptive and innate immune responses. The CD84-CD84 interaction was independent of its cytoplasmic tail. Thus, CD84 is its own ligand and acts as a costimulatory molecule. CD84 is expressed on cells from almost all hematopoietic lineages and on CD34+ hematopoietic progenitor cells, suggesting that CD84 serves as a marker for committed hematopoietic progenitor cells. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human CD84 Protein (TMPY-00715) |
| 抗原种属 | Human |
| 研究领域 | ITIM/ITAM Immunoreceptors and Related Molecules |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
| 存储 | -20°C for 1 year |