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顶部生物活性储存和溶解信息计算器

Anti-Phospho-MAPKAPK2 (Thr334) Polyclonal Antibody 3

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Anti-Phospho-MAPKAPK2 (Thr334) Polyclonal Antibody 3
产品编号 TMAC-02468
别名 p-MAPKAPK2 (Thr334), p-MAPKAPK2 (T334), MAPKAPK2 (p-Thr334), MAPKAPK2 (p-T334)

Anti-Phospho-MAPKAPK2 (Thr334) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-MAPKAPK2 (Thr334)。Anti-Phospho-MAPKAPK2 (Thr334) Polyclonal Antibody 可用于 WB,IHC。

Anti-Phospho-MAPKAPK2 (Thr334) Polyclonal Antibody 3

Anti-Phospho-MAPKAPK2 (Thr334) Polyclonal Antibody 3

Rating icon 还可以
Anti-Phospho-MAPKAPK2 (Thr334) Polyclonal Antibody 3
产品编号 TMAC-02468 别名 p-MAPKAPK2 (Thr334), p-MAPKAPK2 (T334), MAPKAPK2 (p-Thr334), MAPKAPK2 (p-T334)

Anti-Phospho-MAPKAPK2 (Thr334) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-MAPKAPK2 (Thr334)。Anti-Phospho-MAPKAPK2 (Thr334) Polyclonal Antibody 可用于 WB,IHC。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,245
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-MAPKAPK2 (Thr334) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MAPKAPK2 (Thr334). Anti-Phospho-MAPKAPK2 (Thr334) Polyclonal Antibody can be used in WB,IHC.
别名p-MAPKAPK2 (Thr334), p-MAPKAPK2 (T334), MAPKAPK2 (p-Thr334), MAPKAPK2 (p-T334)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of extracts from NIH/3T3 cells, using MAPKAPK2 (Phospho-Thr334) antibody TMAC-02468. The lane on the right is treated with the synthesized peptide.
2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MAPKAPK2 (Phospho-Thr334) antibody TMAC-02468. The picture on the right is treated with the synthesized peptide.
应用
WB
IHC
推荐剂量
WB: 1:500-3000; IHC: 1:50-100
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Stress-activated serine/threonine-protein kinase involved in cytokines production, endocytosis, reorganization of the cytoskeleton, cell migration, cell cycle control, chromatin remodeling, DNA damage response and transcriptional regulation. Following stress, it is phosphorylated and activated by MAP kinase p38-alpha/MAPK14, leading to phosphorylation of substrates. Phosphorylates serine in the peptide sequence, Hyd-X-R-X(2)-S, where Hyd is a large hydrophobic residue. Phosphorylates ALOX5, CDC25B, CDC25C, ELAVL1, HNRNPA0, HSF1, HSP27/HSPB1, KRT18, KRT20, LIMK1, LSP1, PABPC1, PARN, PDE4A, RCSD1, RPS6KA3, TAB3 and TTP/ZFP36. Mediates phosphorylation of HSP27/HSPB1 in response to stress, leading to dissociate HSP27/HSPB1 from large small heat-shock protein (sHsps) oligomers and impair their chaperone activities and ability to protect against oxidative stress effectively.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of threonine 334 (P-Q-T(p)-P-L) derived from Human MAPKAPK2
抗原种属
human
Uniprot ID
P49137
化学信息
分子量Actual: 49 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

pMAPKAPK2 (Thr334)pMAPKAPK2 (T334)MAPKAPK2 (pThr334)MAPKAPK2 (pT334)MAPKAPK2 (phospho-Thr334)MAPKAPK2 (phospho-T334)

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