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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Cullin 2 Antibody (3T657)

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货号 TMAB-04786

Anti-Cullin 2 Antibody (3T657) 是一种 Rabbit 抗体，靶向 Cullin 2。Anti-Cullin 2 Antibody (3T657) 可用于 WB,ICC/IF,IP,FCM。

Anti-Cullin 2 Antibody (3T657)

Anti-Cullin 2 Antibody (3T657)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04786

Anti-Cullin 2 Antibody (3T657) 是一种 Rabbit 抗体，靶向 Cullin 2。Anti-Cullin 2 Antibody (3T657) 可用于 WB,ICC/IF,IP,FCM。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-Cullin 2 Antibody (3T657) is a Rabbit antibody targeting Cullin 2. Anti-Cullin 2 Antibody (3T657) can be used in WB,ICC/IF,IP,FCM.
Ig Type
IgG
克隆号
3T657
反应种属
Human,Mouse (predicted:Rat)
应用WBICC/IFIPFCM
推荐剂量
WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins.
抗原信息
免疫原
A synthesized peptide: human Cullin 2
抗原种属
Human
基因名称
CUL2
基因ID
8453
蛋白名称
Cullin-2
Uniprot ID
Q13617
功能
Core component of multiple cullin-RING-based ECS(ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligasecomplexes, which mediate the ubiquitination of target proteins. Mayserve as a rigid scaffold in the complex and may contribute tocatalysis through positioning of the substrate and theubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligaseactivity of the complex is dependent on the neddylation of thecullin subunit and is inhibited by the association of thedeneddylated cullin subunit with TIP120A/CAND1 (By similarity). Thefunctional specificity of the ECS complex depends on the substraterecognition component. ECS(VHL) mediates the ubiquitination ofhypoxia-inducible factor (HIF).
化学信息
分子量Theoretical: 87 kDa. Actual: 87 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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