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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PGAM5 Polyclonal Antibody

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货号 TMAB-10235

Anti-PGAM5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PGAM5。Anti-PGAM5 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-PGAM5 Polyclonal Antibody

Anti-PGAM5 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-10235

Anti-PGAM5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PGAM5。Anti-PGAM5 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-PGAM5 Polyclonal Antibody is a Rabbit antibody targeting PGAM5. Anti-PGAM5 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrion. Mitochondrion outer membrane. Membrane. Isoform 2 overexpression results in the formation of disconnected punctuate mitochondria distributed throughout the cytoplasm. Isoform 1 overexpression results in the clustering of mitochondria around the nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Members of the PGAM (phosphoglycerate mutase) family of proteins are important components of glucose and 2,3-BPGA (2,3-bisphosphoglycerate) metabolism. They are responsible for catalyzing the transfer of phospho groups between the carbon atoms of phosphoglycerates. PGAM5 (phosphoglycerate mutase family member 5), also known as Bcl-xL-binding protein v68, is a 289 amino acid protein belonging to the BPG-dependent PGAM subfamily. PGAM5 exists as two isoforms produced by alternative splicing events, with isoform two localized to the cytoplasm and isoform one localized to both the cytoplasm and the nucleus. PGAM5 forms a dimer and has been found to interact with Bcl-xS/L and Keap1.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PGAM5
抗原种属
Human
基因名称
PGAM5
基因ID
192111
蛋白名称
Serine/threonine-protein phosphatase PGAM5, mitochondrial
Uniprot ID
Q96HS1
功能
Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression.
化学信息
分子量Theoretical: 32 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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