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Anti-CD2 Antibody (1U731)

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产品编号 TMAY-01423

Anti-CD2 Antibody (1U731) 是一种 Rabbit 抗体,靶向 CD2。Anti-CD2 Antibody (1U731) 可用于 ELISA。

Anti-CD2 Antibody (1U731)

Anti-CD2 Antibody (1U731)

Rating icon 还可以
产品编号 TMAY-01423

Anti-CD2 Antibody (1U731) 是一种 Rabbit 抗体,靶向 CD2。Anti-CD2 Antibody (1U731) 可用于 ELISA。

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产品介绍

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产品描述
Anti-CD2 Antibody (1U731) is a Rabbit antibody targeting CD2. Anti-CD2 Antibody (1U731) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
1U731
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human CD2 (rh CD2; TMPY-01255; NP_001758.2; Met1-Asp209).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景T-cell surface antigen CD2, also known as T-cell surface antigen T11/Leu-5, and SRBC, is a single-pass type I membrane protein. It contains one Ig-like C2-type domain and one Ig-like V-type domain. CD2 is a cell adhesion molecule expressed on T cells and is recognized as a target for CD48 (rats) and CD58 (humans). CD2 has been shown to set quantitative thresholds in T cell activation both in vivo and in vitro. Further, intracellular CD2 signaling pathways and networks are being discovered by the identification of several cytosolic tail binding proteins. CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain of CD2 is implicated in the signaling function. The complex of CD2 and CD58 also plays an important role in enhancing the adhesion of T lymphocytes to target cells, and promoting hyperplasia and activation of T lymphocytes. As a cell surface glycoprotein, CD2 expressed on most human T cells and natural killer (NK) cells and plays an important role in mediating cell adhesion in both T-lymphocytes and in signal transduction.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human CD2 protein (TMPY-01255)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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