Vitamin K4

Name: Vitamin K4
Brand: TargetMol
SKU: T2570
Price: 158 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.84%

货号 T2570Cas号 573-20-6

别名 维生素K4, 维生素 K4, Menadiol Diacetate, Kapilin, acetomenaphthone

Vitamin K4 (Menadiol Diacetate) 是一种维生素药物，用于治疗因缺乏 VK4 引起的凝血障碍。

Vitamin K4

一键复制产品信息

很棒

纯度: 99.84%

货号 T2570 别名 维生素K4, 维生素 K4, Menadiol Diacetate, Kapilin, acetomenaphthoneCas号 573-20-6

Vitamin K4 (Menadiol Diacetate) 是一种维生素药物，用于治疗因缺乏 VK4 引起的凝血障碍。

规格	价格	库存
25 mg	¥ 158	现货
50 mg	¥ 212	现货
100 mg	¥ 293	现货
500 mg	¥ 578	现货
1 g	¥ 752	现货
1 mL x 10 mM (in DMSO)	¥ 457	现货

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COA LCMS HPLC HNMR 产品操作手册

产品介绍

Vitamin K4 AI Summary

Vitamin K4 exhibits a variety of bioactivities, demonstrating potent modulation of lamin A splicing with a potency of 0.8 nM. It also shows inhibitory activities against the malarial parasite plastid, induces DNA re-replication in breast and colon adenocarcinoma cells, and affects Schwann cell intronic elements and viability. Additionally, the compound has activities in assays pertaining to tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibition, acts as a GLP-1 receptor agonist, and inhibits Lassa and Marburg viruses. It has a LogP value of 3.59, indicating moderate lipophilicity, which can influence its bioavailability and distribution. Furthermore, Vitamin K4 exhibits antiviral activity against SARS-CoV-2 by inhibiting the cytotoxicity of VERO-6 cells exposed to the virus, with IC50 values greater than 20000.0 nM and 19952.62 nM in different assays..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Vitamin K4 (Menadiol Diacetate) is a vitamin medicine for the treatment of blood coagulation disorders that caused by the lack of VK4.
别名	维生素K4, 维生素 K4, Menadiol Diacetate, Kapilin, acetomenaphthone

化学信息

分子量	258.27
分子式	C₁₅H₁₄O₄
CAS No.	573-20-6
Smiles	O(C(C)=O)C=1C2=C(C(OC(C)=O)=C(C)C1)C=CC=C2
密度	1.2 g/cm3

储存&溶解度

存储

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 27.5 mg/mL (106.48 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (7.74 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8719 mL	19.3596 mL	38.7192 mL	193.5958 mL
5 mM	0.7744 mL	3.8719 mL	7.7438 mL	38.7192 mL
10 mM	0.3872 mL	1.9360 mL	3.8719 mL	19.3596 mL
20 mM	0.1936 mL	0.9680 mL	1.9360 mL	9.6798 mL
50 mM	0.0774 mL	0.3872 mL	0.7744 mL	3.8719 mL
100 mM	0.0387 mL	0.1936 mL	0.3872 mL	1.9360 mL