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Anti-Hes1 Antibody (4D589) 是一种 Rabbit 抗体,靶向 Hes1。Anti-Hes1 Antibody (4D589) 可用于 WB,ICC/IF,IHC,FCM。
Anti-Hes1 Antibody (4D589) 是一种 Rabbit 抗体,靶向 Hes1。Anti-Hes1 Antibody (4D589) 可用于 WB,ICC/IF,IHC,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,480 | 5日内发货 |
产品描述 | Anti-Hes1 Antibody (4D589) is a Rabbit antibody targeting Hes1. Anti-Hes1 Antibody (4D589) can be used in WB,ICC/IF,IHC,FCM. |
别名 | Transcription factor HES-1., Transcription factor HES 1, RHL, HRY, HL, HHL, Hes1 hairy and enhancer of split 1(Drosophila), HES-1, HES1, hes1, Hairy-like protein, HAIRY1, Hairy/enhancer of split, Drosophila, homolog of, 1, Hairy, Drosophila, homolog of, Hairy like, Hairy homolog(Drosophila), Hairy Homolog, Hairy Enhancer of Split 1, Hairy and enhancer of split 1(Drosophila), Hairy and enhancer of split 1, FLJ20408, Class B basic helix-loop-helix protein 39, c-hairy1A, C-HAIRY1, bHLHb39 |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
应用 | |
推荐剂量 | WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:100-500; FCM: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | The Drosophila Hairy and enhancer of split genes encode basic helix-loop-helix (bHLH) transcriptional repressors that function in the Notch signaling pathway and control segmentation and neural development during embryogenesis. The mammalian homolog of Drosophila Hairy and enhancer of split are the HES gene family members HES1-6, which also encode bHLH transcriptional repressors that regulate myogenesis and neurogenesis. The HES family members form a complex with TLE, the mammalian homolog of groucho, and this interaction is mediated by the carboxy-terminal WRPW motif of the HES proteins. The HES/TLE complex functions by directly binding to DNA instead of interfering with activator proteins. Most HES family members, including HES1 and HES5, preferentially bind to the N box (CACNAG) as opposed to the E box (CANNTG). HES2 binds to both N and E box sites, while HES6 does not bind DNA. Rather, HES6 inhibits HES1 activity, thereby promoting transcription. HES1 and HES2 are expressed in a variety of adult and embryonic tissues. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 30 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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