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Anti-CD1A Antibody (9B433) 是一种 Rabbit 抗体,靶向 CD1A。Anti-CD1A Antibody (9B433) 可用于 WB,IHC。
Anti-CD1A Antibody (9B433) 是一种 Rabbit 抗体,靶向 CD1A。Anti-CD1A Antibody (9B433) 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,485 | 5日内发货 |
产品描述 | Anti-CD1A Antibody (9B433) is a Rabbit antibody targeting CD1A. Anti-CD1A Antibody (9B433) can be used in WB,IHC. |
别名 | T6, R4, HTA1, FCB6, CD1A, CD1 |
Ig Type | IgG |
交叉反应 | Human |
验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD1a antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-CD1a antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:500; IHC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. CD1 antigens are associated with β-2-Microglobulin and expressed on cortical thymocytes, Langerhans cells, a B cell subset and some dendritic cells. Specifically, CD1A is a marker for Langerhans cell histiocytosis (LCH) and is found on interdigitating cells. Adaptor-protein complexes and CD1-associated chaperones control CD1 trafficking, and the development and activation of CD1-restricted T cells. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells. The human CD1 genes are all closely linked in a cluster mapping at chromosome 1q23.1. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 37 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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