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Anti-IL-25/IL17E Antibody (4K762)

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产品编号 TMAY-03142
别名 白细胞介素, 白介素, interleukin 25

Anti-IL-25/IL17E Antibody (4K762) 是一种 Rabbit 抗体,靶向 IL-25/IL17E。Anti-IL-25/IL17E Antibody (4K762) 可用于 ELISA。

Anti-IL-25/IL17E Antibody (4K762)

Anti-IL-25/IL17E Antibody (4K762)

Rating icon 还可以
产品编号 TMAY-03142 别名 白细胞介素, 白介素, interleukin 25

Anti-IL-25/IL17E Antibody (4K762) 是一种 Rabbit 抗体,靶向 IL-25/IL17E。Anti-IL-25/IL17E Antibody (4K762) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,289
5日内发货
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产品介绍

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产品描述
Anti-IL-25/IL17E Antibody (4K762) is a Rabbit antibody targeting IL-25/IL17E. Anti-IL-25/IL17E Antibody (4K762) can be used in ELISA.
别名白细胞介素, 白介素, interleukin 25
Ig Type
Monoclonal Rabbit IgG
克隆号
4K762
交叉反应
Mouse
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL-25 (rM IL-25; TMPY-00855; NP_542767.1; Val 17-Ala 169).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Interleukin-25 (IL-25) is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. IL-25 is a member of the IL-17 family of cytokines. However, unlike the other members of this family, IL-25 promotes T helper (Th) 2 responses. IL-25 also regulates the development of autoimmune inflammation mediated by IL-17–producing T cells. IL-25 and IL-17, being members of the same cytokine family, play opposing roles in the pathogenesis of organ-specific autoimmunity. IL-25 promotes cell expansion and Th2 cytokine production when Th2 central memory cells are stimulated with thymic stromal lymphopoietin (TSLP)–activated dendritic cells (DCs), homeostatic cytokines, or T cell receptor for antigen triggering. Elevated expression of IL-25 and IL-25R transcripts was observed in asthmatic lung tissues and atopic dermatitis skin lesions, linking their possible roles with exacerbated allergic disorders. A plausible explanation that IL-25 produced by innate effector eosinophils and basophils may augment the allergic inflammation by enhancing the maintenance and functions of adaptive Th2 memory cells had been provided.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Mouse IL-25 Protein (TMPY-00855)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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