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Anti-HGFR/c-Met Antibody-APC (4V580)

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货号 TMAY-01071A

别名 MET proto-oncogene, receptor tyrosine kinase

Anti-HGFR/c-Met Antibody-APC (4V580) 是一种 APC-conjugated Rabbit 抗体，靶向 HGFR/c-Met。Anti-HGFR/c-Met Antibody-APC (4V580) 可用于 FCM。

Anti-HGFR/c-Met Antibody-APC (4V580)

Anti-HGFR/c-Met Antibody-APC (4V580)

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货号 TMAY-01071A 别名 MET proto-oncogene, receptor tyrosine kinase

Anti-HGFR/c-Met Antibody-APC (4V580) 是一种 APC-conjugated Rabbit 抗体，靶向 HGFR/c-Met。Anti-HGFR/c-Met Antibody-APC (4V580) 可用于 FCM。

规格价格库存数量
25 T
¥ 690
5日内发货
100 T
¥ 880
5日内发货
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产品介绍

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产品描述
Anti-HGFR/c-Met Antibody-APC (4V580) is a APC-conjugated Rabbit antibody targeting HGFR/c-Met. Anti-HGFR/c-Met Antibody-APC (4V580) can be used in FCM.
别名MET proto-oncogene, receptor tyrosine kinase
Ig Type
Rabbit IgG
克隆号
4V580
反应种属
Human
特异性
Human c-MET/HGFR
验证活性
Profile of anti-human C-Met (HGF R) reactivity on HepG2 cells analyzed by flow cytometry. The Clone 4V580 and 6L502 monoclonal antibodies are not cross-blocking.
应用FCM
推荐剂量
10 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human HGFR / c-MET (rh HGFR / c-MET; TMPY-01296; NP_000236.2; Met 1-Thr 932) and conjugated with APC under optimum conditions, the unreacted APC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR protein is produced as a single-chain precursor, and HGF is the only known ligand. Normal HGF/HGFR signaling is essential for embryonic development, tissue repair, or wound healing, whereas aberrantly active HGFR has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes. HGFR protein is a multifaceted regulator of growth, motility, and invasion, and is normally expressed by cells of epithelial origin. Preclinical studies suggest that targeting aberrant HGFR signaling could be an attractive therapy in cancer.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
APC
其他可选修饰符
Unconjugated/FITC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Protein: Human HGFR / c-MET protein (TMPY-01296)
抗原种属
Human
研究领域
Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs)
储存&溶解度
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
运输方式Shipping with blue ice.
存储keep away from direct sunlight | 4°C for 1 year

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