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Anti-TFPI2 Antibody (8E995) 是一种 Rabbit 抗体,靶向 TFPI2。Anti-TFPI2 Antibody (8E995) 可用于 ELISA,ELISA(Cap)。
Anti-TFPI2 Antibody (8E995) 是一种 Rabbit 抗体,靶向 TFPI2。Anti-TFPI2 Antibody (8E995) 可用于 ELISA,ELISA(Cap)。
产品描述 | Anti-TFPI2 Antibody (8E995) is a Rabbit antibody targeting TFPI2. Anti-TFPI2 Antibody (8E995) can be used in ELISA,ELISA(Cap). |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 8E995 |
交叉反应 | Mouse |
应用 | ELISA,ELISA(Cap) |
推荐剂量 | ELISA: 1:5000-1:10000; ELISA(Cap): 1:250-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse TFPI2 (rM TFPI2; TMPY-02329; O35536; Met1-Lys211). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Tissue factor pathway inhibitor-2 (TFPI2), a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). It is a 32 kDa matrix-associated glycoprotein consisting of a short amino-terminal region, three tandem Kunitz-type domains and a positively charged carboxy-terminal tail. TFPI2 inhibits plasmin-dependent activation of several metalloproteinases. TFPI2 is highly abundant in the full-term placenta and widely expressed in various adult human tissues, such as the liver, skeletal muscle, heart, kidney, and pancreas. The expression of TFPI2 in tumors is inversely related to an increasing degree of malignancy, which may suggest a role for TFPI2 in the maintenance of tumor stability and inhibition of the growth of neoplasms. TFPI2 inhibits the tissue factor/factor VIIa (TF/VIIa) complex and a wide variety of serine proteinases including plasmin, plasma kallikrein, factor XIa, trypsin, and chymotrypsin. TFPI2 is involved in regulating pericellular proteases implicated in a variety of physiologic and pathologic processes including cancer cell invasion, vascular inflammation, and atherosclerosis. TFPI2 has also been shown to induce apoptosis and inhibit angiogenesis, which may contribute significantly to tumor growth inhibition. |
偶联 | Unconjugated |
免疫原 | Recombinant Mouse TFPI2 protein (TMPY-02329) |
抗原种属 | Mouse |
研究领域 | Serine Proteases and Regulators |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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