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Anti-human CD47 Antibody (3B549)

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货号 TMAB-07412

Anti-human CD47 Antibody (3B549) 是一种 Mouse 抗体，靶向 human CD47。Anti-human CD47 Antibody (3B549) 可用于 FCM。

Anti-human CD47 Antibody (3B549)

Anti-human CD47 Antibody (3B549)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07412

Anti-human CD47 Antibody (3B549) 是一种 Mouse 抗体，靶向 human CD47。Anti-human CD47 Antibody (3B549) 可用于 FCM。

规格价格库存数量
100 μg
¥ 1,875
5日内发货
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产品介绍

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产品描述
Anti-human CD47 Antibody (3B549) is a Mouse antibody targeting human CD47. Anti-human CD47 Antibody (3B549) can be used in FCM.
Ig Type
Mouse IgG1, k
克隆号
3B549
反应种属
Human
应用FCM
推荐剂量
FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cell membrane; Multi-pass membrane protein.
组织特异性Very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4).
研究背景This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]
抗原信息
基因名称
CD47
基因ID
961
蛋白名称
Leukocyte surface antigen CD47
功能
Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.
化学信息
分子量Theoretical: 33 kDa. Actual: 42-52 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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