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NSC 694623 是一种有效的组蛋白乙酰转移酶 (HAT) 抑制剂,对重组 HAT p300/CBP 相关因子 (PCAF) 具有抑制作用,IC50 为 15.9 μM。NSC 694623 对部分癌细胞展示出抗增殖活性,可用于研究抗癌。
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NSC 694623 是一种有效的组蛋白乙酰转移酶 (HAT) 抑制剂,对重组 HAT p300/CBP 相关因子 (PCAF) 具有抑制作用,IC50 为 15.9 μM。NSC 694623 对部分癌细胞展示出抗增殖活性,可用于研究抗癌。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 396 | 现货 | |
5 mg | ¥ 937 | 现货 | |
10 mg | ¥ 1,380 | 现货 | |
25 mg | ¥ 2,320 | 现货 | |
50 mg | ¥ 3,460 | 现货 | |
100 mg | ¥ 4,910 | 现货 |
产品描述 | NSC 694623 is a potent histone acetyltransferase (HAT) inhibitor with IC50 of 15.9 μM against recombinant HAT p300/CBP associated factor (PCAF). NSC 694623 shows anti-proliferative activity against some cancer cells, which can be used for anti-cancer research. |
靶点活性 | PCAF:15.9 μM |
体外活性 | NSC 694623 exhibits antiproliferative activity against SK-N-SH cells, with an IC50 value of 8.93 μM. Additionally, it inhibits 21% of HCT116 cells at a concentration of 25 μM.[1] |
分子量 | 284.38 |
分子式 | C16H16N2OS |
CAS No. | 907957-34-0 |
存储 | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 112.5 mg/mL (395.6 mM), Sonication and heating to 60℃ are recommended. | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO
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