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Anti-HCN3 Polyclonal Antibody

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货号 TMAB-06918

Anti-HCN3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HCN3。Anti-HCN3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-HCN3 Polyclonal Antibody

Anti-HCN3 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06918

Anti-HCN3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HCN3。Anti-HCN3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-HCN3 Polyclonal Antibody is a Rabbit antibody targeting HCN3. Anti-HCN3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Cow,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Hyperpolarization-activated, cyclic nucleotide-binding channels (HCN) are voltage-gated cation channels that are activated by direct binding of intracellular cyclic nucleotides. The HCN family consists of four members (HCN1-4), each with a core transmembrane segment domain and a C-terminal 120 amino-acid cyclic nucleotide-binding domain motif. HCN channels are expressed in the brain, heart, thalamus and testis. The pacemaker properties of HCN channels contribute to spontaneous rhythmic activity in the brain and heart. HCN3 contains a segment characterized by a series of positively charged amino acids at every third position. This region designated S4 is likely to be the voltage sensor of the protein. In the brain, HCN3 and HCN4 exhibit subcortical distribution mainly concentrated in the hypothalamus and thalamus, respectively.
抗原信息
免疫原
KLH conjugated synthetic peptide: human HCN3
抗原种属
Human
基因名称
HCN3
基因ID
蛋白名称
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
Uniprot ID
功能
Putative hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions (By similarity).
化学信息
分子量Theoretical: 86 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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