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Anti-HCN3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HCN3。Anti-HCN3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-HCN3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HCN3。Anti-HCN3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-HCN3 Polyclonal Antibody is a Rabbit antibody targeting HCN3. Anti-HCN3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat,Cow,Horse,Rabbit) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane; Multi-pass membrane protein. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Hyperpolarization-activated, cyclic nucleotide-binding channels (HCN) are voltage-gated cation channels that are activated by direct binding of intracellular cyclic nucleotides. The HCN family consists of four members (HCN1-4), each with a core transmembrane segment domain and a C-terminal 120 amino-acid cyclic nucleotide-binding domain motif. HCN channels are expressed in the brain, heart, thalamus and testis. The pacemaker properties of HCN channels contribute to spontaneous rhythmic activity in the brain and heart. HCN3 contains a segment characterized by a series of positively charged amino acids at every third position. This region designated S4 is likely to be the voltage sensor of the protein. In the brain, HCN3 and HCN4 exhibit subcortical distribution mainly concentrated in the hypothalamus and thalamus, respectively. |
| 免疫原 | KLH conjugated synthetic peptide: human HCN3 |
| 抗原种属 | Human |
| 基因名称 | HCN3 |
| 基因ID | |
| 蛋白名称 | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 |
| Uniprot ID | |
| 功能 | Putative hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions (By similarity). |
| 分子量 | Theoretical: 86 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |