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Anti-ICAM-2/CD102 Antibody (9W742)
还可以产品编号 TMAY-00621
Anti-ICAM-2/CD102 Antibody (9W742) 是一种 Mouse 抗体，靶向 ICAM-2/CD102。Anti-ICAM-2/CD102 Antibody (9W742) 可用于 IHC-P。
Anti-ICAM-2/CD102 Antibody (9W742)
Anti-ICAM-2/CD102 Antibody (9W742)
还可以产品编号 TMAY-00621
Anti-ICAM-2/CD102 Antibody (9W742) 是一种 Mouse 抗体，靶向 ICAM-2/CD102。Anti-ICAM-2/CD102 Antibody (9W742) 可用于 IHC-P。
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抗原信息
| 产品描述 | Anti-ICAM-2/CD102 Antibody (9W742) is a Mouse antibody targeting ICAM-2/CD102. Anti-ICAM-2/CD102 Antibody (9W742) can be used in IHC-P. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 9W742 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human ICAM2 in human spleen with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to vascular endothelial cells. 2. Immunochemical staining of human ICAM2 in human kidney with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to vascular endothelial cells. |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:50-1:200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ICAM-2 / CD102 (rh ICAM-2 / CD102; TMPY-01418; NP_000864.2; Met1-Gln223). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Intercellular adhesion molecule 2 (ICAM-2, CD102), belongs to the ICAM family consisting of three members identified as ligands for integrin receptors. It is a type I transmembrane glycoprotein with two Ig-like C2-type domains and binds to the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). As the second ligand of leukocyte function-associated antigen-1, ICAM-2 functions as a costimulatory molecule for effector cells. ICAM-2 is mainly expressed on vascular endothelial and hematopoietic cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocyte with other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity, and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relationship with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in the diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human ICAM-2 / CD102 protein (TMPY-01418) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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