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Anti-AXIN2 Antibody (6U272) 是一种 Rabbit 抗体,靶向 AXIN2。Anti-AXIN2 Antibody (6U272) 可用于 WB,ICC/IF,IHC。
Anti-AXIN2 Antibody (6U272) 是一种 Rabbit 抗体,靶向 AXIN2。Anti-AXIN2 Antibody (6U272) 可用于 WB,ICC/IF,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,490 | 5日内发货 |
产品描述 | Anti-AXIN2 Antibody (6U272) is a Rabbit antibody targeting AXIN2. Anti-AXIN2 Antibody (6U272) can be used in WB,ICC/IF,IHC. |
Ig Type | IgG |
克隆号 | 6U272 |
交叉反应 | Human,Mouse,Rat |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC: 1:10-50; ICC/IF: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | b-catenin is a component of both the cadherin cell adhesion system and the Wnt signaling pathway. Wnt signaling increases the amount of b-catenin, by preventing its ubiquitination and degradation, allowing its direct interaction with transcription factors of the lymphoid enhancer factor-T cell factor family and modulation of gene expression. Axin is involved in the degradation of b-catenin by acting as a scaffold to form a complex between b-catenin, adenomatous polyposis coli (APC) and GSK-3b. APC, which is phosphorylated by GSK-3b, induces degradation of b-catenin, thus inhibiting Wnt signal transduction. Conductin is 45% identical to axin and appears to play a similar role to axin in the Wnt signaling pathway. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 94 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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