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Anti-Gastrokine 1 Antibody (4C630)
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产品编号 TMAY-02817
别名 UNQ489/PRO1005, gastrokine 1, foveolin, FOV, CA11, BRICD1, AMP18
Anti-Gastrokine 1 Antibody (4C630) 是一种 Mouse 抗体，靶向 Gastrokine 1。Anti-Gastrokine 1 Antibody (4C630) 可用于 ELISA。
Anti-Gastrokine 1 Antibody (4C630)
Anti-Gastrokine 1 Antibody (4C630)
还可以产品编号 TMAY-02817 别名 UNQ489/PRO1005, gastrokine 1, foveolin, FOV, CA11, BRICD1, AMP18
Anti-Gastrokine 1 Antibody (4C630) 是一种 Mouse 抗体，靶向 Gastrokine 1。Anti-Gastrokine 1 Antibody (4C630) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,684 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Gastrokine 1 Antibody (4C630) is a Mouse antibody targeting Gastrokine 1. Anti-Gastrokine 1 Antibody (4C630) can be used in ELISA. |
| 别名 | UNQ489/PRO1005, gastrokine 1, foveolin, FOV, CA11, BRICD1, AMP18 |
| Ig Type | Mouse IgG1 |
| 克隆号 | 4C630 |
| 交叉反应 | Human |
| 应用 | |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GKN1 / Gastrokine 1 (rh GKN1 / Gastrokine 1; TMPY-00519; Q9NS71; Asn35-Asn199). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Gastrokine 1 (GKN1) belongs to the BRICHOS domain family and plays a major role in maintaining gastric mucosa integrity. GKN1 is highly expressed in gastric tissue and is secreted into the stomach but is not expressed in gastric cancer. GKN1-mediated inhibition of APP processing might represent a new approach for the prevention and therapy of Alzheimer's disease (AD). In the presence of GKN2, GKN1 loses its ability to decrease cell proliferation, induce apoptosis, and inhibit epigenetic alterations in gastric cancer cells, that GKN2 may contribute to the homeostasis of gastric epithelial cells by inhibiting GKN1 activity. The loss of GKN1 function contributes to malignant transformation and proliferation of gastric epithelial cells in gastric carcinogenesis. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human GKN1 / Gastrokine 1 Protein (TMPY-00519) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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