Name: Frexalimab
Brand: TargetMol
SKU: T77013
Price: 3290 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 3,290

现货

5 mg

¥ 7,260

现货

10 mg

¥ 9,790

现货

25 mg

¥ 14,500

现货

50 mg

¥ 19,600

现货

生物活性

产品描述	Frexalimab (SAR441344) is a second-generation humanized monoclonal antibody targeting CD40L. It blocks the CD40/CD40L signaling pathway to reduce inflammation and tissue damage, making it applicable for autoimmune diseases such as primary Sjögren's syndrome, systemic lupus erythematosus, and multiple sclerosis.
体外活性	Frexalimab 是一种经过Fc改造的第二代抗CD40L人源化单克隆抗体，其Fc改造能够消除由免疫复合物刺激FcγRIIa引发的血小板活化[2]。
别名	伏沙利单抗, SAR-441344, SAR441344, INX-021, INX021
反应种属	Human
应用	ELISA FACS Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1.0 EU/mg

抗体信息

同型

IgG1-ARA

偶联与修饰

偶联	Unconjugated

抗原信息

Uniprot ID	P29965
靶点	CD40

化学信息

CAS No.

2515463-86-0

储存&溶解度

存储	-20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准

Frexalimab