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Anti-CTHRC1 Antibody (3C604)
还可以产品编号 TMAY-03845
Anti-CTHRC1 Antibody (3C604) 是一种 Rabbit 抗体，靶向 CTHRC1。Anti-CTHRC1 Antibody (3C604) 可用于 ELISA。
Anti-CTHRC1 Antibody (3C604)
Anti-CTHRC1 Antibody (3C604)
还可以产品编号 TMAY-03845
Anti-CTHRC1 Antibody (3C604) 是一种 Rabbit 抗体，靶向 CTHRC1。Anti-CTHRC1 Antibody (3C604) 可用于 ELISA。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-CTHRC1 Antibody (3C604) is a Rabbit antibody targeting CTHRC1. Anti-CTHRC1 Antibody (3C604) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 3C604 |
| 交叉反应 | Rat |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Rat CTHRC1 (rR CTHRC1; TMPY-04288; NP_001258229.1; Met1-Lys230). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Collagen triple helix repeat-containing protein 1, also known as Protein NMTC1, and CTHRC1, is a secreted protein that is glycosylated and highly conserved from lower chordates to mammals. CTHRC1 expression was not detectable in normal arteries. However, it is transiently expressed in the arterial wall in response to injury where it may contribute to vascular remodeling by limiting collagen matrix deposition and promoting cell migration. A short collagen motif with 12 Gly-X-Y repeats appears to be responsible for trimerization of the CTHRC1 protein and this renders the molecule susceptible to cleavage by collagenase. CTHRC1 overexpression caused a dramatic reduction in collagen type I mRNA and protein levels. Currently available data indicate that Cthrc1 expression in vascular cells regulates transforming growth factor beta responsiveness, thereby impacting transforming growth factor beta target genes, including collagens. Additionally, CTHRC1 increases bone mass as a positive regulator of osteoblastic bone formation and offers an anabolic approach for the treatment of osteoporosis. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Rat CTHRC1 Protein (TMPY-04288) |
| 抗原种属 | Rat |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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