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Anti-PRDM5 Antibody (2C105)

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Anti-PRDM5 Antibody (2C105)
产品编号 TMAC-03414
别名 PRDM5_HUMAN, PRDM5 protein, PRDM 5, PR domain-containing protein 5, PR domain zinc finger protein 5, PR domain containing protein 5, PR domain containing 5, PFM2, PFM 2, BCS2

Anti-PRDM5 Antibody (2C105) 是一种 Mouse 抗体,靶向 PRDM5。Anti-PRDM5 Antibody (2C105) 可用于 WB,ICC,FCM。

Anti-PRDM5 Antibody (2C105)

Anti-PRDM5 Antibody (2C105)

Rating icon 还可以
Anti-PRDM5 Antibody (2C105)
产品编号 TMAC-03414 别名 PRDM5_HUMAN, PRDM5 protein, PRDM 5, PR domain-containing protein 5, PR domain zinc finger protein 5, PR domain containing protein 5, PR domain containing 5, PFM2, PFM 2, BCS2

Anti-PRDM5 Antibody (2C105) 是一种 Mouse 抗体,靶向 PRDM5。Anti-PRDM5 Antibody (2C105) 可用于 WB,ICC,FCM。

规格价格库存数量
50 μL
¥ 1,990
5日内发货
100 μL
¥ 2,995
5日内发货
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产品介绍

生物活性
产品描述
Anti-PRDM5 Antibody (2C105) is a Mouse antibody targeting PRDM5. Anti-PRDM5 Antibody (2C105) can be used in WB,ICC,FCM.
别名PRDM5_HUMAN, PRDM5 protein, PRDM 5, PR domain-containing protein 5, PR domain zinc finger protein 5, PR domain containing protein 5, PR domain containing 5, PFM2, PFM 2, BCS2
交叉反应
Human,Mouse
验证活性
1. Western blot analysis of PRDM5 on human PRDM5 recombinant protein using anti-PRDM5 antibody at 1/1,000 dilution.
2. Western blot analysis of PRDM5 on HEK293 (1) and PRDM5-hIgGFc transfected HEK293 (2) cell lysate using anti-PRDM5 antibody at 1/1,000 dilution.
3. ICC staining PRDM5 (green) and Actin filaments (red) in MCF-7 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. Flow cytometric analysis of Hela cells with PRDM5 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
应用
推荐剂量
WB: 1:1000-2000; ICC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景A cDNA of PRDM5 was isolated based upon its homology to the PR domain of PRDM2. The gene encodes an open reading frame of 630 amino acids and contains a PR domain in the NH-terminal region followed by 16 zinc finger motifs. Through radiation hybrid analysis, PRDM5 was mapped to human chromosome 4q27, a region thought to contain tumor suppressor genes for ovarian, breast, lung, liver, colon, and other cancers. The gene has a CpG island promoter and is silenced in human breast, ovarian, and liver cancers. Upon infection of tumor cells, a recombinant adenovirus expressing PRDM5 causes G2/M arrest and apoptosis, suggesting that inhibition of PRDM5 may be involved in carcinogenesis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 73 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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