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顶部生物活性储存和溶解信息计算器

Anti-Phospho-NTRK2 (Tyr817) Antibody (6J201)

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Anti-Phospho-NTRK2 (Tyr817) Antibody (6J201)
产品编号 TMAC-03281
别名 p-NTRK2 (Y817), p-NTRK2 (Tyr817), NTRK2 (p-Y817), NTRK2 (p-Tyr817)

Anti-Phospho-NTRK2 (Y817) Antibody (6J201) 是一种 Rabbit 抗体，靶向 Phospho-NTRK2 (Y817)。Anti-Phospho-NTRK2 (Y817) Antibody (6J201) 可用于 WB,ICC/IF,IHC,IP。

Anti-Phospho-NTRK2 (Tyr817) Antibody (6J201)

Anti-Phospho-NTRK2 (Tyr817) Antibody (6J201)

Rating icon 还可以
Anti-Phospho-NTRK2 (Tyr817) Antibody (6J201)
产品编号 TMAC-03281 别名 p-NTRK2 (Y817), p-NTRK2 (Tyr817), NTRK2 (p-Y817), NTRK2 (p-Tyr817)

Anti-Phospho-NTRK2 (Y817) Antibody (6J201) 是一种 Rabbit 抗体，靶向 Phospho-NTRK2 (Y817)。Anti-Phospho-NTRK2 (Y817) Antibody (6J201) 可用于 WB,ICC/IF,IHC,IP。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-NTRK2 (Tyr817) Antibody (6J201) 是一种 Rabbit 抗体，靶向 Phospho-NTRK2 (Tyr817)。Anti-Phospho-NTRK2 (Tyr817) Antibody (6J201) 可用于 WB,ICC/IF,IHC,IP。
别名p-NTRK2 (Y817), p-NTRK2 (Tyr817), NTRK2 (p-Y817), NTRK2 (p-Tyr817)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of phospho-TrkB (Y817) on mouse brain lysates using anti-phospho-TrkB (Y817) antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-phospho-TrkB (Y817) antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-phospho-TrkB (Y817) antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-phospho-TrkB (Y817) antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue using anti-phospho-TrkB (Y817) antibody. Counter stained with hematoxylin.
6. ICC staining phospho-TrkB (Y817) in PANC-1 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
7. ICC staining phospho-TrkB (Y817) in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC/IF
IHC
IP
推荐剂量
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The Trk proto-oncogene encodes a tyrosine protein kinase, Trk A, also designated Trk gp140, that serves as a receptor for certain neurotrophic factors including nerve growth factor (NGF) and neurotrophin-3 (NT-3). Trk B is a tyrosine kinase gene highly related to Trk A. Trk B expression is confined to tissues within the central and peripheral nervous systems. The brain-derived neurotrophic factor (BDNF) and NT-3, but not NGF, can induce rapid phosphorylation on tyrosine of Trk B gp145, one of the receptors encoded by NTRK2, although BDNF elicits a response at least two orders of magnitude greater than NT-3. Thus it appears that Trk B gp145 may represent a neurotrophic receptor for BDNF and NT-3. The third member of the Trk family of tyrosine kinases, Trk C, encodes a protein designated Trk C gp145 that is preferentially expressed in brain tissue, is equally related to Trk A and Trk B and is a functional receptor for NT-3.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
A synthesized phosphopeptide: human TrkB around the phosphorylation site of Tyr817
抗原种属
human
Uniprot ID
Q16620
化学信息
分子量Theoretical: 145 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

pNTRK2 (Y817)pNTRK2 (Tyr817)NTRK2 (pY817)NTRK2 (pTyr817)NTRK2 (phospho-Y817)NTRK2 (phospho-Tyr817)

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