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Anti-IL-18BP Antibody (4Q496)
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产品编号 TMAY-00682
别名 interleukin 18 binding protein, IL18BPa
Anti-IL-18BP Antibody (4Q496) 是一种 Mouse 抗体，靶向 IL-18BP。Anti-IL-18BP Antibody (4Q496) 可用于 ELISA,ELISA(Cap)。
Anti-IL-18BP Antibody (4Q496)
Anti-IL-18BP Antibody (4Q496)
还可以产品编号 TMAY-00682 别名 interleukin 18 binding protein, IL18BPa
Anti-IL-18BP Antibody (4Q496) 是一种 Mouse 抗体，靶向 IL-18BP。Anti-IL-18BP Antibody (4Q496) 可用于 ELISA,ELISA(Cap)。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μL | ¥ 795 | 5日内发货 | |
| 100 μL | ¥ 2,289 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-IL-18BP Antibody (4Q496) is a Mouse antibody targeting IL-18BP. Anti-IL-18BP Antibody (4Q496) can be used in ELISA,ELISA(Cap). |
| 别名 | interleukin 18 binding protein, IL18BPa |
| Ig Type | Mouse IgG2b |
| 克隆号 | 4Q496 |
| 交叉反应 | Human |
| 应用 | ELISA,ELISA(Cap) |
| 推荐剂量 | ELISA: 1:1000-1:2000; ELISA(Cap): 1:250-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL18BPa N-terminal domain (rhIL18BPa; TMPY-00846; NP_001034748.1; Met1-Gly194). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Interleukin-18-binding protein (IL-18BP) is a constitutively expressed and secreted protein. IL-18BP is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18) and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. The adjacently located family members IL18 Receptor 1 (IL18R1) and IL18 receptor accessory protein (IL18RAP) may also be important in the development of asthma and atopy. IL-18 binding protein (IL-18BP) was only moderately elevated, resulting in a high level of biologically active free IL-18 in HPS. A severe IL-18/IL-18BP imbalance results in Th-1 lymphocyte and macrophage activation, which escapes control by NK-cell cytotoxicity and may allow for secondary HPS in patients with underlying diseases. |
| 偶联 | Unconjugated |
| 免疫原 | Human cell-derived rhIL18BPa (TMPY-00846) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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