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顶部生物活性储存和溶解信息计算器

Anti-IL-18BP Antibody (4Q496)

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产品编号 TMAY-00682

别名 interleukin 18 binding protein, IL18BPa

Anti-IL-18BP Antibody (4Q496) 是一种 Mouse 抗体，靶向 IL-18BP。Anti-IL-18BP Antibody (4Q496) 可用于 ELISA,ELISA(Cap)。

Anti-IL-18BP Antibody (4Q496)

Anti-IL-18BP Antibody (4Q496)

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产品编号 TMAY-00682 别名 interleukin 18 binding protein, IL18BPa

Anti-IL-18BP Antibody (4Q496) 是一种 Mouse 抗体，靶向 IL-18BP。Anti-IL-18BP Antibody (4Q496) 可用于 ELISA,ELISA(Cap)。

规格价格库存数量
20 μL
¥ 795
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100 μL
¥ 2,289
5日内发货
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产品介绍

生物活性
产品描述
Anti-IL-18BP Antibody (4Q496) is a Mouse antibody targeting IL-18BP. Anti-IL-18BP Antibody (4Q496) can be used in ELISA,ELISA(Cap).
别名interleukin 18 binding protein, IL18BPa
Ig Type
Mouse IgG2b
克隆号
4Q496
交叉反应
Human
特异性
Human IL-18BP
应用ELISAELISA(Cap)
推荐剂量
ELISA: 1:1000-1:2000; ELISA(Cap): 1:250-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL18BPa N-terminal domain (rhIL18BPa; TMPY-00846; NP_001034748.1; Met1-Gly194). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Interleukin-18-binding protein (IL-18BP) is a constitutively expressed and secreted protein. IL-18BP is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18) and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. The adjacently located family members IL18 Receptor 1 (IL18R1) and IL18 receptor accessory protein (IL18RAP) may also be important in the development of asthma and atopy. IL-18 binding protein (IL-18BP) was only moderately elevated, resulting in a high level of biologically active free IL-18 in HPS. A severe IL-18/IL-18BP imbalance results in Th-1 lymphocyte and macrophage activation, which escapes control by NK-cell cytotoxicity and may allow for secondary HPS in patients with underlying diseases.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Human cell-derived rhIL18BPa (TMPY-00846)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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