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Anti-Phospho-IL7R (Tyr449) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-IL7R (Tyr449)。Anti-Phospho-IL7R (Tyr449) Polyclonal Antibody 可用于 WB,FCM。
Anti-Phospho-IL7R (Tyr449) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-IL7R (Tyr449)。Anti-Phospho-IL7R (Tyr449) Polyclonal Antibody 可用于 WB,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-Phospho-IL7R (Tyr449) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IL7R (Tyr449). Anti-Phospho-IL7R (Tyr449) Polyclonal Antibody can be used in WB,FCM. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse) |
| 应用 | WBFCM |
| 推荐剂量 | WB: 1:500-2000; FCM: 2μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted and Cell membrane. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). |
| 免疫原 | KLH conjugated Synthesised phosphopeptide: human IL-7Ra around the phosphorylation site of Tyr449 |
| 抗原种属 | Human |
| 基因名称 | IL7R |
| 基因ID | |
| 蛋白名称 | Interleukin-7 receptor subunit alpha |
| Uniprot ID | |
| 功能 | Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP). |
| 分子量 | Theoretical: 48 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |