Name: Bebtelovimab
Brand: TargetMol
SKU: T78252
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

1 mg

¥ 2,490

2-4周

5 mg

¥ 6,470

2-4周

10 mg

¥ 9,870

2-4周

生物活性

产品描述	Bebtelovimab (LY-CoV1404) is a neutralizing, fully human IgG1 monoclonal antibody targeting the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein. This product binds specifically to a highly conserved epitope on the RBD, blocking the interaction between the spike protein and the human angiotensin-converting enzyme 2 (ACE2) receptor. Bebtelovimab exhibits potent and broad neutralizing activity against various SARS-CoV-2 variants, including Omicron (BA.1/BA.2), Delta, and other earlier strains. In clinical settings, it is utilized to reduce the risk of severe disease progression in high-risk ambulatory patients, such as solid organ transplant recipients.
体外活性	在生化实验中，Bebtelovimab 以高亲和力结合 SARS-CoV-2 RBD 上的保守表位。它通过防止病毒尖峰蛋白与宿主 ACE2 受体结合，有效中和了原始株及包括 Delta 和 Omicron 在内的多种关注变异株 [2]。
别名	贝特洛韦单抗, LY-COV1404, LY-3853113
反应种属	Virus
应用	ELISA FACS Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1.0 EU/mg

抗体信息

同型

IgG1

偶联与修饰

偶联	Unconjugated

抗原信息

Uniprot ID	P0DTC2
靶点	SARS-CoV-2

化学信息

CAS No.

2578319-11-4

储存&溶解度

存储

Bebtelovimab