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Anti-Coagulation Factor VIII/FVIII/F8 Polyclonal Antibody

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货号 TMAB-00453

别名 THPH13, HEMA, FVIII, F8C, F8B, DXS1253E, AHF

Anti-Coagulation Factor VIII/FVIII/F8 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Coagulation Factor VIII/FVIII/F8。Anti-Coagulation Factor VIII/FVIII/F8 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

Anti-Coagulation Factor VIII/FVIII/F8 Polyclonal Antibody

Anti-Coagulation Factor VIII/FVIII/F8 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-00453 别名 THPH13, HEMA, FVIII, F8C, F8B, DXS1253E, AHF

Anti-Coagulation Factor VIII/FVIII/F8 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Coagulation Factor VIII/FVIII/F8。Anti-Coagulation Factor VIII/FVIII/F8 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Coagulation Factor VIII/FVIII/F8 Polyclonal Antibody is a Rabbit antibody targeting Coagulation Factor VIII/FVIII/F8. Anti-Coagulation Factor VIII/FVIII/F8 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
别名THPH13, HEMA, FVIII, F8C, F8B, DXS1253E, AHF
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Rabbit)
验证活性
Paraformaldehyde-fixed, paraffin embedded (rat brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (factor VIII) Polyclonal Antibody, Unconjugated (TMAB-00453) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
verifiedActivity
应用IFIHC-FrIHC-P
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted, extracellular space.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: rat factor VIII
抗原种属
Rat
基因名称
F8
蛋白名称
Coagulation factor VIII
研究领域
Intrinsic
功能
Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa.
化学信息
分子量Theoretical: 267 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

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