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Anti-CCR4 Antibody (2Q459) 是一种抗体,靶向 CCR4。Anti-CCR4 Antibody (2Q459) 可用于 ELISA,FCM。
Anti-CCR4 Antibody (2Q459) 是一种抗体,靶向 CCR4。Anti-CCR4 Antibody (2Q459) 可用于 ELISA,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,310 | 5日内发货 | |
| 100 μL | ¥ 2,190 | 5日内发货 |
| 产品描述 | Anti-CCR4 Antibody (2Q459) is an antibody targeting CCR4. Anti-CCR4 Antibody (2Q459) can be used in ELISA,FCM. |
| Ig Type | Human IgG1 |
| 克隆号 | 2Q459 |
| 交叉反应 | Human |
| 验证活性 | 1. The Binding Activity of CCR4 with Anti-CCR4 Recombinant Antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized CCR4 at 10 μg/mL can bind Anti-CCR4 Recombinant Antibody, the EC50 is 362.3-630.8 ng/mL. 2. Untransfected HEK293 cells surface (green line) and transfected Human CCR4 HEK293 stable cells surface (red line) were stained with anti-CCR4 antibody(2µl/1*10^6 cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry. |
| 应用 | ELISAFCM |
| 推荐剂量 | FCM:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | Predominantly expressed in the thymus, in peripheral blood leukocytes, including T-cells, mostly CD4+ cells, and basophils, and in platelets; at lower levels, in the spleen and in monocytes. Detected also in macrophages, IL-2-activated natural killer cell |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| 研究背景 | High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human CCR4 Protein |
| 抗原种属 | Human |
| 基因名称 | CCR4 |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Immunology |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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