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Anti-Claudin-2 Polyclonal Antibody
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产品编号 TMAB-00441
Anti-Claudin-2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Claudin-2。Anti-Claudin-2 Polyclonal Antibody 可用于 WB。
Anti-Claudin-2 Polyclonal Antibody
Anti-Claudin-2 Polyclonal Antibody
还可以产品编号 TMAB-00441
Anti-Claudin-2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Claudin-2。Anti-Claudin-2 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-Claudin-2 Polyclonal Antibody is a Rabbit antibody targeting Claudin-2. Anti-Claudin-2 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 交叉反应 | Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| 验证活性 | Sample: A549 (Human) Cell Lysate at 30 μg Primary: Anti-Claudin 2 (TMAB-00441) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 25 kDa Observed band size: 25 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell junction; tight junction. Cell membrane. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | The claudin superfamily consists of structurally related proteins that are important structural and functional components of tight junctions. Claudin-2, also known as CLDN2 or SP82, is a 230 amino acid multi-pass membrane protein that localizes to the cell junctions and belongs to the claudin superfamily. Able to form homopolymers of heteropolymers with other claudin family members, claudin-2 plays an essential role in mediating calcium-independent cell-adhesion activity that is necessary for tight junction-specific obliteration of the intercellular space. Overexpression of claudin-2 is associated with a variety of diseases, including lung cancer, colorectal cancer, gastrointestinal carcinomas and inflammatory bowel disease, further affirming the importance of claudin-2 in cell adhesion. The gene encoding claudin-2 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. |
| 免疫原 | KLH conjugated synthetic peptide: human Claudin 2 |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Tight Junctions |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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