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Anti-BASP1 Antibody (4A217) 是一种 Mouse 抗体,靶向 BASP1。Anti-BASP1 Antibody (4A217) 可用于 ELISA。
Anti-BASP1 Antibody (4A217) 是一种 Mouse 抗体,靶向 BASP1。Anti-BASP1 Antibody (4A217) 可用于 ELISA。
产品描述 | Anti-BASP1 Antibody (4A217) is a Mouse antibody targeting BASP1. Anti-BASP1 Antibody (4A217) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG2b |
克隆号 | 4A217 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human BASP1 (P80723; aa3-227). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | The AML1-ETO fusion protein (A/E), which results from the t(8;21) translocation, is considered to be a leukemia-initiating event. Identifying the mechanisms underlying the oncogenic activity of A/E remains a major challenge. BASP1 silencing via promoter methylation may be involved in A/E-mediated leukemogenesis and that BASP1 targeting may be an actionable therapeutic strategy in t(8;21) AML. BASP1 is a novel prognostic factor for patients with cervical cancer, and promotes the proliferation and tumorigenicity of cervical cancer. BASP1 acts as a major selectivity factor in the transcriptional response of breast cancer cells to tamoxifen. |
偶联 | Unconjugated |
免疫原 | Recombinant Human BASP1 Protein |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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