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Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc)

产品编号 TMPY-02515

别名: IFN-alphaJ, 干扰素, IFNA-J, IFN-αJ, interferon, alpha 7, interferon, α7

Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48 kDa and the accession number is P01567.

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Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc)

规格	价格/CNY		货期	数量
100 μg	￥ 1,750		现货

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参考文献

生物活性	Measured in antiviral assays using WISH human amnion cells infected with vesicular stomatitisvirus (VSV). The ED50 for this effect is 0.1-1 ng/mL.
产品描述	Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48 kDa and the accession number is P01567.

种属	Human
表达系统	HEK293 Cells
标签	N-hFc
蛋白编号	P01567
别名	IFN-alphaJ, 干扰素, IFNA-J, IFN-αJ, interferon, alpha 7, interferon, α7
蛋白构建	The Human IFNA7 (P01567) (Cys 24-Asp 189) was fused with the Fc region of Human IgG1 at the N-terminus.
蛋白纯度	> 85 % as determined by SDS-PAGE
分子量	48 kDa (predicted)

内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Interferon alpha-7(IFNA7) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a consequence of the cause answer by different inductors. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs have other functions: they activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes, and they increase the ability of uninfected host cells to resist new infection by the virus. Certain host symptoms, such as aching muscles and fever, are related to the production of IFNs during infection. Human IFN is divided on the sequence of amino-acids into three groups: Alpha, Beta, and Gamma interferons.

参考文献

1. De Veer MJ, et al. (2001) Functional classification of interferon-stimulated genes identified using microarrays. J Leukoc Biol. 69 (6): 912-20. 2. Liu YJ. (2005) IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. Annu Rev Immunol. 23: 275-306. 3. Fensterl V, et al. (2009) Interferons and viral infections. Biofactors. 35 (1): 14-20.

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Keywords

Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc) IFN-alphaJ 干扰素 IFNA-J interferon, α 7 IFN-αJ interferon, a 7 interferon, alpha 7 interferon, α7 recombinant recombinant-proteins proteins protein

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