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S100A2 Protein, Human, Recombinant

S100A2 Protein, Human, Recombinant

产品编号 TMPY-00998
别名: S100L, CAN19, S100 calcium binding protein A2

S100A2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 11 kDa and the accession number is P29034.

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S100A2 Protein, Human, Recombinant
规格 价格/CNY 货期 数量
100 μg ¥ 4,460 5日内发货
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产品目录号及名称: S100A2 Protein, Human, Recombinant (TMPY-00998)
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生物活性 Testing in progress
产品描述 S100A2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 11 kDa and the accession number is P29034.
种属 Human
表达系统 E. coli
标签 Tag Free
蛋白编号 P29034
别名 S100L, CAN19, S100 calcium binding protein A2
蛋白构建 Human S100A2 (NP_005969.1) (Met 2-Pro 98)
蛋白纯度 > 95 % as determined by SDS-PAGE
分子量 11 kDa (predicted)
内毒素 Please contact us for more information.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 The calcium-binding protein S100A2 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 family genes are located as a cluster on chromosome 1q21, and S100 proteins consisting of at least 20 members are involved in the regulation of a number of cellular processes such as cell-cycle progression and cell differentiation. S100A2 was first detected in lung and kidney, and is mainly expressed in a subset of tissues and cells such as breast epithelia and liver. The S100A2 protein is a homodimer that undergoes a conformational change upon binding of calcium, and the active form functions in regulating cell proliferation and differentiation, gene transcription, and p53-dependent growth arrest and apoptosis. Accordingly, this protein is regarded as a putative tumor suppressor, and thus chromosomal rearrangements and reduced expression of S100A2 gene have been implicated in certain carcinomas.

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Keywords

S100A2 Protein, Human, Recombinant S100L CAN-19 CAN19 S100 calcium binding protein A2 CAN 19 recombinant recombinant-proteins proteins protein

 

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