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Anti-MELK Antibody (8J637) 是一种 Rabbit 抗体,靶向 MELK。Anti-MELK Antibody (8J637) 可用于 WB。
Anti-MELK Antibody (8J637) 是一种 Rabbit 抗体,靶向 MELK。Anti-MELK Antibody (8J637) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 790 | 5日内发货 | |
| 50 μL | ¥ 1,395 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-MELK Antibody (8J637) is a Rabbit antibody targeting MELK. Anti-MELK Antibody (8J637) can be used in WB. |
| Ig Type | IgG |
| 克隆号 | 8J637 |
| 反应种属 | Human |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Expressed in placenta, kidney, thymus, testis, ovary and intestine. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation. Has a broad substrate specificity; phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622. Acts as an activator of apoptosis by phosphorylating and activating MAP3K5/ASK1. Acts as a regulator of cell cycle, notably by mediating phosphorylation of CDC25B, promoting localization of CDC25B to the centrosome and the spindle poles during mitosis. |
| 免疫原 | A synthesized peptide: human MELK |
| 抗原种属 | Human |
| 基因名称 | MELK |
| 基因ID | |
| 蛋白名称 | Maternal embryonic leucine zipper kinase |
| Uniprot ID | |
| 功能 | Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis. |
| 分子量 | Theoretical: 75 kDa. Actual: 75 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |