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Anti-Decorin Antibody (2P567)
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产品编号 TMAY-00429
别名 SLRR1B, PGS2, PGII, PG40, DSPG2, decorin, CSCD
Anti-Decorin Antibody (2P567) 是一种 Rabbit 抗体，靶向 Decorin。Anti-Decorin Antibody (2P567) 可用于 ELISA。
Anti-Decorin Antibody (2P567)
331 Anti-Decorin Antibody (2P567)
还可以产品编号 TMAY-00429 别名 SLRR1B, PGS2, PGII, PG40, DSPG2, decorin, CSCD
Anti-Decorin Antibody (2P567) 是一种 Rabbit 抗体，靶向 Decorin。Anti-Decorin Antibody (2P567) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,284 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Decorin Antibody (2P567) is a Rabbit antibody targeting Decorin. Anti-Decorin Antibody (2P567) can be used in ELISA. |
| 别名 | SLRR1B, PGS2, PGII, PG40, DSPG2, decorin, CSCD |
| Ig Type | Rabbit IgG |
| 克隆号 | 2P567 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Decorin (rh Decorin; TMPY-01608; NP_001911.1; Met 1-Lys 359). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core protein and a covalently linked glycosaminoglycan chain which is either chondroitin sulfate (CS) or dermatan sulfate (DS). As a component of connective tissue, decorin interacts with several extracellular matrix components, such as type I collagen and fibronectin, and plays a role in matrix assembly. Decorin resides in the tumor microenvironment and affects the biology of various types of cancer by downregulating the activity of several receptors involved in cell growth and survival. Decorin binds to and modulates the signaling of the epidermal growth factor receptor and other members of the ErbB family of receptor tyrosine kinases. It exerts its antitumor activity by a dual mechanism: via inhibition of these key receptors through their physical downregulation coupled with attenuation of their signaling, and by binding to and sequestering TGFbeta. Decorin also modulates the insulin-like growth factor receptor and the low-density lipoprotein receptor-related protein 1, which indirectly affects the TGFbeta receptor pathway. Decorin plays significant roles in tissue development and assembly, as well as playing both direct and indirect signaling roles. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human Decorin protein (TMPY-01608) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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