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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-TNFRSF10A Polyclonal Antibody

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货号 TMAB-13634

Anti-TNFRSF10A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TNFRSF10A。Anti-TNFRSF10A Polyclonal Antibody 可用于 WB。

Anti-TNFRSF10A Polyclonal Antibody

Anti-TNFRSF10A Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-13634

Anti-TNFRSF10A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TNFRSF10A。Anti-TNFRSF10A Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-TNFRSF10A Polyclonal Antibody is a Rabbit antibody targeting TNFRSF10A. Anti-TNFRSF10A Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
组织特异性Widely expressed. High levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K562 erythroleukemia cells, MCF7 breast carcinoma cells and activated T-cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
Recombinant Protein: human DR4 protein
抗原种属
Human
基因名称
TNFRSF10A
基因ID
8797
蛋白名称
Tumor necrosis factor receptor superfamily member 10A
Uniprot ID
O00220
功能
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.
化学信息
分子量Theoretical: 50 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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