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Anti-LIMPII/SR-B2 Antibody-FITC (7J773) 是一种 FITC-conjugated Rabbit 抗体,靶向 LIMPII/SR-B2。Anti-LIMPII/SR-B2 Antibody-FITC (7J773) 可用于 FCM。
Anti-LIMPII/SR-B2 Antibody-FITC (7J773) 是一种 FITC-conjugated Rabbit 抗体,靶向 LIMPII/SR-B2。Anti-LIMPII/SR-B2 Antibody-FITC (7J773) 可用于 FCM。
产品描述 | Anti-LIMPII/SR-B2 Antibody-FITC (7J773) is a FITC-conjugated Rabbit antibody targeting LIMPII/SR-B2. Anti-LIMPII/SR-B2 Antibody-FITC (7J773) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 7J773 |
交叉反应 | Mouse |
验证活性 | Flow cytometric analysis of Mouse SCARB2 expression in spleen lymphocytes. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and then stained with FITC Rabbit anti-Mouse SCARB2. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
应用 | FCM |
推荐剂量 | 10 μl/Test, 0.1 mg/ml |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse LIMP-2 / SCARB2 / CD36L2 (rM LIMP-2 / SCARB2 / CD36L2; TMPY-01434; NP_031670.1; Met1-Thr432) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
研究背景 | Lysosomal Integral Membrane Protein II (LIMPII), also known as SCARB2, LPG85, and CD36L2, is a type I II multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. This protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. LIMPII is identified as a receptor for EV71 (human enterovirus species A, Enterovirus 71) and CVA16 (coxsackievirus A16) which are most frequently associated with hand, foot and mouth disease (HFMD). Expression of human LIMPII enables normally unsusceptible cell lines to support the viruses’ propagation and develop cytopathic effects. In addition, LIMPII also has been shown to bind thrombospondin-1, and may contribute to the pro-adhesive changes of activated platelets during coagulation, and inflammation. Deficiency of the protein in mice impairs cell membrane transport processes and causes pelvic junction obstruction, deafness, and peripheral neuropathy. |
偶联 | FITC |
其他可选修饰符 | Unconjugated/APC/PE |
可提供抗体种类 | 4 |
免疫原 | Recombinant Mouse LIMP-2 / SCARB2 / CD36L2 protein (TMPY-01434) |
抗原种属 | Mouse |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
运输方式 | Shipping with blue ice. |
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