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别名 RCK, Probable ATP-dependent RNA helicase DDX6, Oncogene RCK, HLR2, EC 3.6.4.13, DEAD box protein 6, ATP-dependent RNA helicase p54
Anti-DDX6 Antibody (4N492) 是一种抗体,靶向 DDX6。Anti-DDX6 Antibody (4N492) 可用于 ELISA,IHC。
Anti-DDX6 Antibody (4N492) 是一种抗体,靶向 DDX6。Anti-DDX6 Antibody (4N492) 可用于 ELISA,IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,310 | 5日内发货 | |
| 100 μL | ¥ 2,190 | 5日内发货 |
| 产品描述 | Anti-DDX6 Antibody (4N492) is an antibody targeting DDX6. Anti-DDX6 Antibody (4N492) can be used in ELISA,IHC. |
| 别名 | RCK, Probable ATP-dependent RNA helicase DDX6, Oncogene RCK, HLR2, EC 3.6.4.13, DEAD box protein 6, ATP-dependent RNA helicase p54 |
| Ig Type | Rabbit IgG |
| 克隆号 | 4N492 |
| 交叉反应 | Human |
| 验证活性 | IHC image of TMAH-00339 diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| 应用 | ELISAIHC |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cytoplasm, P-body. Cytoplasm. Nucleus. |
| 组织特异性 | Abundantly expressed in most tissues. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Essential for the formation of P-bodies, cytosolic membrane-less ribonucleoprotein granules involved in RNA metabolism through the coordinated storage of mRNAs encoding regulatory functions. Plays a role in P-bodies to coordinate the storage of translationally inactive mRNAs in the cytoplasm and prevent their degradation. In the process of mRNA degradation, plays a role in mRNA decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human DDX6 |
| 抗原种属 | Human |
| 基因名称 | DDX6 |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Epigenetics and Nuclear Signaling |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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