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PCSK9 Protein, Human, Recombinant (Avi), Biotinylated

Synonyms: Subtilisin/Kexin-Like Protease PC9, Proprotein Convertase Subtilisin/Kexin Type 9, Proprotein Convertase 9, PCSK9, PC9, Neural Apoptosis-Regulated Convertase 1, NARC-1, NARC1
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PCSK9 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 19&65 KDa and the accession number is Q8NBP7.

PCSK9 Protein, Human, Recombinant (Avi), Biotinylated

一键复制产品信息
Rating icon 还可以
202603开学季活动
货号 TMPJ-00368

别名 Subtilisin/Kexin-Like Protease PC9, Proprotein Convertase Subtilisin/Kexin Type 9, Proprotein Convertase 9, PCSK9, PC9, Neural Apoptosis-Regulated Convertase 1, NARC-1, NARC1

PCSK9 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 19&65 KDa and the accession number is Q8NBP7.

PCSK9 Protein, Human, Recombinant (Avi), Biotinylated
其他形式的 “PCSK9 Protein, Human, Recombinant (Avi), Biotinylated”:
规格价格库存数量
10 μg
¥ 1,350
35日内发货
20 μg
¥ 2,260
35日内发货
50 μg
¥ 3,980
35日内发货
100 μg
¥ 6,130
35日内发货
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选择批次:
纯度: Greater than 95% as determined by reducing SDS-PAGE.
颜色: 无色透明
性状: Liquid
资源下载: COA重组蛋白用户指南

产品介绍


生物活性
产品描述
PCSK9 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 19&65 KDa and the accession number is Q8NBP7.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels. PCSK9 also binds to apolipoprotein receptor 2 (ApoER2), and play a role in the neural development.
种属
Human
表达系统
HEK293 Cells
标签
C-Avi
蛋白编号Q8NBP7
氨基酸序列
Gln31-Gln692(Val474Ile,Gly670Glu)
蛋白构建
Gln31-Gln692(Val474Ile,Gly670Glu)
蛋白纯度
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
缓冲液
Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, 20% Glycerol, pH 7.4.
别名
Subtilisin/Kexin-Like Protease PC9, Proprotein Convertase Subtilisin/Kexin Type 9, Proprotein Convertase 9, PCSK9, PC9, Neural Apoptosis-Regulated Convertase 1, NARC-1, NARC1
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量19&65 KDa (reducing condition)
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
  • 比活力 计算器

剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.
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