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Anti-15-PGDH Antibody-HRP (6U764)

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产品编号 TMAY-01751H
别名 hydroxyprostaglandin dehydrogenase 15-(NAD), AV026552, 15-PGDH

Anti-15-PGDH Antibody-HRP (6U764) 是一种 HRP-conjugated Rabbit 抗体,靶向 15-PGDH。Anti-15-PGDH Antibody-HRP (6U764) 可用于 ELISA。

Anti-15-PGDH Antibody-HRP (6U764)

Anti-15-PGDH Antibody-HRP (6U764)

Rating icon 还可以
产品编号 TMAY-01751H 别名 hydroxyprostaglandin dehydrogenase 15-(NAD), AV026552, 15-PGDH

Anti-15-PGDH Antibody-HRP (6U764) 是一种 HRP-conjugated Rabbit 抗体,靶向 15-PGDH。Anti-15-PGDH Antibody-HRP (6U764) 可用于 ELISA。

规格价格库存数量
100 μg
¥ 3,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-15-PGDH Antibody-HRP (6U764) is a HRP-conjugated Rabbit antibody targeting 15-PGDH. Anti-15-PGDH Antibody-HRP (6U764) can be used in ELISA.
别名hydroxyprostaglandin dehydrogenase 15-(NAD), AV026552, 15-PGDH
Ig Type
Monoclonal Rabbit IgG
克隆号
6U764
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 0.1-1 μg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human HPGD / 15-PGDH (rh HPGD / 15-PGDH; TMPY-01264; NP_000851.2; Met1-Gln266), and conjugated with horseradish-peroxidase (HRP).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景15-hydroxyprostaglandin dehydrogenase [NAD+], also known as Prostaglandin dehydrogenase 1, HPGD, and PGDH1, is a member of the short-chain dehydrogenases/reductases (SDR) family. Prostaglandins (PGs) play a key role in the onset of labor in many species and regulate uterine contractility and cervical dilatation. Therefore, the regulation of prostaglandin output by PG synthesizing and metabolizing enzymes in the human myometrium may determine uterine activity patterns in human labor both at preterm and at term. Prostaglandin dehydrogenase (PGDH) metabolizes prostaglandins (PGs) to render them inactive. HPGD is down-regulated by cortisol, dexamethasone, and betamethasone and down-regulated in colon cancer. It is up-regulated by TGFB1. HPGD contributes to the regulation of events that are under the control of prostaglandin levels. HPGD catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. and inhibits in vivo proliferation of colon cancer cells. Defects in HPGD are the cause of primary hypertrophic osteoarthropathy autosomal recessive (PHOAR), cranio-osteoarthropathy (COA), and isolated congenital nail clubbing.
偶联与修饰
偶联
HRP
其他可选修饰符
Unconjugated
可提供抗体种类
2
抗原信息
免疫原
Recombinant Human HPGD / 15-PGDH protein (TMPY-01264)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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