规格

价格

库存

数量

1 mg

¥ 1,150

现货

5 mg

¥ 2,850

现货

10 mg

¥ 3,970

现货

25 mg

¥ 5,920

现货

50 mg

¥ 8,160

现货

100 mg

¥ 10,900

现货

500 mg

¥ 22,100

现货

1 mL x 10 mM (in DMSO)

¥ 3,220

现货

生物活性

产品描述	Bidisomide (SC40230) is an agent of class I antiarrhythmic.
体内活性	Bidisomide's anti-arrhythmia effects. Bidisomide (5 mg/kg) reduces the number of premature ventricular complexes and the incidence of ventricular tachycardia and ventricular fibrillation similarly to Mexiletine (MXT) and Disopyramide (DSP) in rats with ventricular arrhythmias induced by coronary artery occlusion. After 5 minutes of coronary artery occlusion, the antiarrhythmic effect of 5 mg/kg Bidisomide was similar to the same dose of MXT and DSP in rats with ventricular arrhythmias caused by coronary reperfusion. All three drugs significantly slow the heart rate[1].
别名	比地索胺, SC40230

化学信息

分子量	407.98
分子式	C₂₂H₃₄ClN₃O₂
CAS No.	116078-65-0
Smiles	CC(C)N(CCC(CCN1CCCCC1)(C(N)=O)c1ccccc1Cl)C(C)=O
密度	1.124g/cm3

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 225 mg/mL (551.5 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (12.26 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO