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Anti-MEK3 Antibody (1C515) 是一种 Rabbit 抗体,靶向 MEK3。Anti-MEK3 Antibody (1C515) 可用于 WB。
Anti-MEK3 Antibody (1C515) 是一种 Rabbit 抗体,靶向 MEK3。Anti-MEK3 Antibody (1C515) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 780 | 5日内发货 | |
| 50 μL | ¥ 1,390 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
| 产品描述 | Anti-MEK3 Antibody (1C515) is a Rabbit antibody targeting MEK3. Anti-MEK3 Antibody (1C515) can be used in WB. |
| Ig Type | IgG |
| 克隆号 | 1C515 |
| 反应种属 | Human (predicted:Mouse,Rat) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm; cytoskeleton. |
| 组织特异性 | Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq]. |
| 免疫原 | KLH conjugated synthetic peptide: human MEK3 |
| 抗原种属 | Human |
| 基因名称 | MAP2K3 |
| 基因ID | |
| 蛋白名称 | Dual specificity mitogen-activated protein kinase kinase 3 |
| Uniprot ID | |
| 功能 | Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. |
| 分子量 | Theoretical: 39 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |