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Anti-MEK3 Antibody (1C515)

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货号 TMAB-08735

Anti-MEK3 Antibody (1C515) 是一种 Rabbit 抗体,靶向 MEK3。Anti-MEK3 Antibody (1C515) 可用于 WB。

Anti-MEK3 Antibody (1C515)

Anti-MEK3 Antibody (1C515)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08735

Anti-MEK3 Antibody (1C515) 是一种 Rabbit 抗体,靶向 MEK3。Anti-MEK3 Antibody (1C515) 可用于 WB。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍


生物活性
产品描述
Anti-MEK3 Antibody (1C515) is a Rabbit antibody targeting MEK3. Anti-MEK3 Antibody (1C515) can be used in WB.
Ig Type
IgG
克隆号
1C515
反应种属
Human (predicted:Mouse,Rat)
应用WB
推荐剂量
WB: 1:500-1000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm; cytoskeleton.
组织特异性Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq].
抗原信息
免疫原
KLH conjugated synthetic peptide: human MEK3
抗原种属
Human
基因名称
MAP2K3
基因ID
蛋白名称
Dual specificity mitogen-activated protein kinase kinase 3
Uniprot ID
功能
Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.
化学信息
分子量Theoretical: 39 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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