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Anti-SEMA4D Antibody (5F505)
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产品编号 TMAH-01083
别名 Semaphorin-4D, SEMAJ, SEMA4D, M-sema-G, MGC169141, MGC169138, FLJ46484, FLJ39737, FLJ34282, FLJ33485, coll-4, CD100, C9orf164
Anti-SEMA4D Antibody (5F505) 是一种抗体，靶向 SEMA4D。Anti-SEMA4D Antibody (5F505) 可用于 ELISA, FCM。
Anti-SEMA4D Antibody (5F505)
Anti-SEMA4D Antibody (5F505)
还可以产品编号 TMAH-01083 别名 Semaphorin-4D, SEMAJ, SEMA4D, M-sema-G, MGC169141, MGC169138, FLJ46484, FLJ39737, FLJ34282, FLJ33485, coll-4, CD100, C9orf164
Anti-SEMA4D Antibody (5F505) 是一种抗体，靶向 SEMA4D。Anti-SEMA4D Antibody (5F505) 可用于 ELISA, FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,300 | 5日内发货 | |
| 100 μL | ¥ 2,190 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-SEMA4D Antibody (5F505) is an antibody targeting SEMA4D. Anti-SEMA4D Antibody (5F505) can be used in ELISA, FCM. |
| 别名 | Semaphorin-4D, SEMAJ, SEMA4D, M-sema-G, MGC169141, MGC169138, FLJ46484, FLJ39737, FLJ34282, FLJ33485, coll-4, CD100, C9orf164 |
| Ig Type | Human IgG4(S228P) |
| 克隆号 | 5F505 |
| 交叉反应 | Human, Mouse |
| 验证活性 | 1. The Binding Activity of Mouse Sema4d with Anti-SEMA4D recombinant antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Anti-SEMA4D recombinant antibody at 2 μg/mL can bind Mouse Sema4d, the EC50 is 5.829-16.86 ng/mL. 2. The Binding Activity of Human SEMA4D with Anti-SEMA4D recombinant antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human SEMA4D at 2 μg/mL can bind Anti- SEMA4D recombinant antibody, the EC50 is 60.38-152.6 ng/mL. 3. Untransfected HEK293T cells surface (green line) and transfected Human SEMA4D HEK293T stable cells surface (red line) were stained with anti-SEMA4D antibody (2µg/1*10^6 cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry. |
| 应用 | |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| 研究背景 | Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling. Regulates GABAergic synapse development. Promotes the development of inhibitory synapses in a PLXNB1-dependent manner. Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA. Promotes the migration of cerebellar granule cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human SEMA4D Protein |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Immunology |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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