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Anti-Periostin/OSF-2 Polyclonal Antibody

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货号 TMAB-01371

别名 PN, periostin, osteoblast specific factor, periostin, PDLPOSTN, OSF-2, OSF2

Anti-Periostin/OSF-2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Periostin/OSF-2。Anti-Periostin/OSF-2 Polyclonal Antibody 可用于 ELISA,IF,IHC-Fr,IHC-P,WB。

Anti-Periostin/OSF-2 Polyclonal Antibody

Anti-Periostin/OSF-2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-01371 别名 PN, periostin, osteoblast specific factor, periostin, PDLPOSTN, OSF-2, OSF2

Anti-Periostin/OSF-2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Periostin/OSF-2。Anti-Periostin/OSF-2 Polyclonal Antibody 可用于 ELISA,IF,IHC-Fr,IHC-P,WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-Periostin/OSF-2 Polyclonal Antibody is a Rabbit antibody targeting Periostin/OSF-2. Anti-Periostin/OSF-2 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB.
别名PN, periostin, osteoblast specific factor, periostin, PDLPOSTN, OSF-2, OSF2
Ig Type
IgG
反应种属
(predicted:Human,Mouse,Rat,Pig,Cow,Horse,Rabbit)
应用ELISAIFIHC-FrIHC-PWB
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted, extracellular space, extracellular matrix.
组织特异性Widely expressed with highest levels in aorta, stomach, lower gastrointestinal tract, placenta, uterus and breast. Up-regulated in epithelial ovarian tumors. Not expressed in normal ovaries. Also highly expressed at the tumor periphery of lung carcinoma t
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Periostin is a disulfide linked 90 kDa, 811 amino acid protein originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta 1(TGF beta 1) and bone morphogenetic protein (BMP2). Periostin has a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain and a C-terminal domain. The fourfold repeated domain of OSF2 shows homology with the insect protein fasciclin. Periostin mRNA is expressed in the developing mouse embryonic and fetal heart, and that it is localized to the endocardial cushions that ultimately divide the primitive heart tube into a four-chambered heart. Abnormal expression of periostin is also linked to angiogenesis and metastatsis in epithelial tumors.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Periostin.
抗原种属
Human
基因名称
POSTN
基因ID
蛋白名称
Periostin
Uniprot ID
研究领域
Extracellular matrix,Cell adhesion molecules,Cardiomyocyte precursors,Bone,Focal Adhesions,Other Cell Types
功能
Binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization.
化学信息
分子量Theoretical: 100 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

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