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Anti-ACVR2A Polyclonal Antibody

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货号 TMAB-02268

Anti-ACVR2A Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ACVR2A。Anti-ACVR2A Polyclonal Antibody 可用于 WB。

Anti-ACVR2A Polyclonal Antibody

Anti-ACVR2A Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-02268

Anti-ACVR2A Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ACVR2A。Anti-ACVR2A Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-ACVR2A Polyclonal Antibody is a Rabbit antibody targeting ACVR2A. Anti-ACVR2A Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse,Rat
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex (1). Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (also designated ACVR2A) or ACTR-IIB (also designated ACVR2B) (1-6). Both receptor types are highly expressed in brain (5). The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morpho- genesis in a dose dependent fashion (5,6).
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse ACVR2A
抗原种属
Mouse
基因名称
ACVR2A
基因ID
蛋白名称
Activin receptor type-2A
Uniprot ID
功能
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
化学信息
分子量Theoretical: 57 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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