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Anti-TRP1 Antibody (9T409)
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产品编号 TMAC-04140
别名 TYRRP, TYRP, TRP1, TRP, OCA3, GP75, CATB, CAS2, b-PROTEIN
Anti-TRP1 Antibody (9T409) 是一种 Rabbit 抗体，靶向 TRP1。Anti-TRP1 Antibody (9T409) 可用于 WB,ICC,IHC,IP。
Anti-TRP1 Antibody (9T409)
Anti-TRP1 Antibody (9T409)
还可以产品编号 TMAC-04140 别名 TYRRP, TYRP, TRP1, TRP, OCA3, GP75, CATB, CAS2, b-PROTEIN
Anti-TRP1 Antibody (9T409) 是一种 Rabbit 抗体，靶向 TRP1。Anti-TRP1 Antibody (9T409) 可用于 WB,ICC,IHC,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
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抗原信息
化学信息
| 产品描述 | Anti-TRP1 Antibody (9T409) is a Rabbit antibody targeting TRP1. Anti-TRP1 Antibody (9T409) can be used in WB,ICC,IHC,IP. |
| 别名 | TYRRP, TYRP, TRP1, TRP, OCA3, GP75, CATB, CAS2, b-PROTEIN |
| Ig Type | IgG |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of TRP1 on melanoma tissue lysate using anti-TRP1 antibody at 1/500 dilution. 2. Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-TRP1 antibody. Counter stained with hematoxylin. 3. ICC staining TRP1 in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining TRP1 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-100; IP: 1:10-50 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Tyrosinase (TYR), a type I membrane protein and copper-containing enzyme, is involved in the production of melanin, the primary pigment found in vertebrates. Melanin biogenesis requires the enzymatic activity of TYR, which catalyzes the critical and rate-limiting step of tyrosine hydroxylation in the biosynthesis of melanin. Defects effecting TYR activity result in various forms of albinism. The TYR-related proteins, TRP1 and TRP2, are also specifically expressed in melanocytes, and they likewise contribute to the synthesis of melanin within the melanosomes. The TRPs, including TYR, all share a similar transmembrane region, contain two metal-binding regions and a cysteine-rich epidermal growth factor motif, and are localized in the melanosomal membrane. These proteins, however, have distinct catalytic activity, and they individually contribute to the biosynthesis of melanin biopolymers. The TRPs are believed to exists as a multi-enzyme complex, as these proteins form aggregates together, and the expression of TRP1 also helps stabilize TYR in melanocytes. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 72 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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