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Anti-GDF-15 Antibody (2W692) 是一种抗体,靶向 GDF-15。Anti-GDF-15 Antibody (2W692) 可用于 ELISA, IHC。
Anti-GDF-15 Antibody (2W692) 是一种抗体,靶向 GDF-15。Anti-GDF-15 Antibody (2W692) 可用于 ELISA, IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,305 | 5日内发货 | |
100 μL | ¥ 2,195 | 5日内发货 |
产品描述 | Anti-GDF-15 Antibody (2W692) is an antibody targeting GDF-15. Anti-GDF-15 Antibody (2W692) can be used in ELISA, IHC. |
别名 | RG-1, PTGF-β, PTGFBPTGF-β, PTGFBPTGF-beta, PTGF-beta, PTGFB, Placental TGF-β, Placental TGF-beta, PLAB, PDF, NAG-1, MIC-1, MIC1, GDF-15, GDF15 |
Ig Type | Rabbit IgG |
克隆号 | 2W692 |
交叉反应 | Human |
验证活性 | IHC image of TMAH-00481 diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
应用 | ELISA, IHC |
推荐剂量 | IHC:1:50-1:200. |
抗体种类 | Monoclonal |
亚细胞定位 | Secreted. |
构建方式 | Recombinant Antibody |
纯化方式 | Affinity-chromatography |
性状 | Liquid |
缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem. It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which constitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions. On hepatocytes, inhibits growth hormone signaling. |
偶联 | Unconjugated |
免疫原 | A synthetic peptide: Human GDF15 |
抗原种属 | Human |
基因ID | 9518 |
Uniprot ID | |
研究领域 | Cardiovascular, Cell biology, Signal transduction |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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