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Anti-ITGB1 Antibody (1I859) 是一种 Rabbit 抗体,靶向 ITGB1。Anti-ITGB1 Antibody (1I859) 可用于 WB,IHC。
Anti-ITGB1 Antibody (1I859) 是一种 Rabbit 抗体,靶向 ITGB1。Anti-ITGB1 Antibody (1I859) 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,490 | 5日内发货 |
产品描述 | Anti-ITGB1 Antibody (1I859) is a Rabbit antibody targeting ITGB1. Anti-ITGB1 Antibody (1I859) can be used in WB,IHC. |
别名 | VLA-β, VLA-BETA, VLAB, MSK12, MDF2, integrin, β1 (fibronectin receptor, βpolypeptide, antigen CD29 includes MDF2, MSK12), integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12), Integrin β1, GPIIA, FNRB, CD29 |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat,zebrafish |
验证活性 | 1. Western blot analysis of Integrin beta 1 on different cell lysates using anti-Integrin beta 1 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: NIH/3T3. 2. Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-Integrin beta 1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-Integrin beta 1 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse stomach tissue using anti-Integrin beta 1 antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:1000-5000; IHC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Integrins are transmembrane receptors that mediate the attachment between a cell and its surroundings, such as other cells or the extracellular matrix (ECM). Integrins are obligate heterodimers containing two distinct chains, called the α (alpha) and β (beta) subunits. The molecular mass of the integrin subunits can vary from 90 kDa to 160 kDa. Beta subunits have four cysteine-rich repeated sequences. Both α and β subunits bind several divalent cations. Integrins have two main functions: Attachment of the cell to the ECM and signal transduction from the ECM to the cell. However, they are also involved in a wide range of other biological activities, including immune patrolling, cell migration, and binding to cells by certain viruses, such as adenovirus, echovirus, hantavirus, and foot and mouth disease viruses. Research studies have implicated β1 integrin in various activities including embryonic development, blood vessel, skin, bone, and muscle formation, as well as tumor metastasis and angiogenesis. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 140 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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