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Anti-Phospho-DDIT3 (Ser30) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-DDIT3 (Ser30)。Anti-Phospho-DDIT3 (Ser30) Polyclonal Antibody 可用于 WB。
Anti-Phospho-DDIT3 (Ser30) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-DDIT3 (Ser30)。Anti-Phospho-DDIT3 (Ser30) Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,230 | 5日内发货 |
产品描述 | Anti-Phospho-DDIT3 (Ser30) Polyclonal Antibody is a Rabbit antibody targeting Phospho-DDIT3 (Ser30). Anti-Phospho-DDIT3 (Ser30) Polyclonal Antibody can be used in WB. |
别名 | p-DDIT3 (Ser30), p-DDIT3 (S30), DDIT3 (p-Ser30), DDIT3 (p-S30) |
Ig Type | IgG |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of extracts from Jurkat cells treated with PMA using Phospho-CHOP (Ser30) antibody TMAC-00851. The lane on the right is treated with the antigen-specific peptide. |
应用 | |
推荐剂量 | WB: 1:500-1000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression of C/EBP regulated genes. Positively regulates the transcription of TRIB3, IL6, IL8, IL23, TNFRSF10B/DR5, PPP1R15A/GADD34, BBC3/PUMA, BCL2L11/BIM and ERO1L. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of serine30(V-L-S(p)-S-D) derived from Human CHOP |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 19 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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