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Anti-S100P Antibody (1S30)
还可以产品编号 TMAY-02402
别名 S100 calcium binding protein P, MIG9
Anti-S100P Antibody (1S30) 是一种 Rabbit 抗体，靶向 S100P。Anti-S100P Antibody (1S30) 可用于 IHC-P,ICC/IF。
Anti-S100P Antibody (1S30)
Anti-S100P Antibody (1S30)
还可以产品编号 TMAY-02402 别名 S100 calcium binding protein P, MIG9
Anti-S100P Antibody (1S30) 是一种 Rabbit 抗体，靶向 S100P。Anti-S100P Antibody (1S30) 可用于 IHC-P,ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,294 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-S100P Antibody (1S30) is a Rabbit antibody targeting S100P. Anti-S100P Antibody (1S30) can be used in IHC-P,ICC/IF. |
| 别名 | S100 calcium binding protein P, MIG9 |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 1S30 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human S100P in human spleen with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human S100P in human placenta with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). The image showing nucleus staining of trophoblastic cells. 3. Immunofluorescence staining of S100P in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-Y S100P monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®594-conjugated Goat Anti-rabbit IgG secondary antibody (red). Positive staining was localized to Nucleus and Cytoplasm. |
| 应用 | IHC-P,ICC/IF |
| 推荐剂量 | IHC-P: 1:100-1:500; ICC-IF: 1:20-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human S100P (rh S100P; TMPY-02216; P25815; Met1-Lys95). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Protein S100-P, also known as Protein S100-E, S100 calcium-binding protein P, S100P and S100E, is a nucleus and cytoplasm protein that belongs to the S-100 family. S100P / S100E contains twoEF-hand domains. S100P protein regulates calcium signal transduction and mediates cytoskeletal interaction, protein phosphorylation and transcriptional control. S100P / S100E overexpression can upregulate androgen receptor expression and thereby promote prostate cancer progression by increasing cell growth. S100P / S100E may directly confer resistance to chemotherapy. S100P / S100E induction may be considered an important step in the initial stage of lung adenocarcinomas, whereas its downregulation in advanced stages seems to be important for tumour progression in which DNA methylation and/or feedback transcription processes play a critical role. S100P / S100E plays a major role in the aggressiveness of pancreatic cancer that is likely mediated by its ability to activate RAGE. Interference with S100P / S100E may provide a novel approach for treatment of pancreatic cancer. S100P / S100E could be considered a potential drug target or a chemosensitization target, and could also serve as a biomarker for aggressive, hormone-refractory and metastatic prostate cancer. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human S100P protein (TMPY-02216) |
| 抗原种属 | Human |
| 研究领域 | Calcium-binding Proteins and Related Molecules |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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