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Anti-mouse CD3 Antibody (8I639)

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货号 TMAB-08953

Anti-mouse CD3 Antibody (8I639) 是一种 Rat 抗体，靶向 mouse CD3。Anti-mouse CD3 Antibody (8I639) 可用于 FCM。

Anti-mouse CD3 Antibody (8I639)

Anti-mouse CD3 Antibody (8I639)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08953

Anti-mouse CD3 Antibody (8I639) 是一种 Rat 抗体，靶向 mouse CD3。Anti-mouse CD3 Antibody (8I639) 可用于 FCM。

规格价格库存数量
100 μg
¥ 1,870
5日内发货
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产品介绍

生物活性
产品描述
Anti-mouse CD3 Antibody (8I639) is a Rat antibody targeting mouse CD3. Anti-mouse CD3 Antibody (8I639) can be used in FCM.
Ig Type
Rat IgG2b, k
克隆号
8I639
反应种属
Mouse
应用FCM
推荐剂量
FCM: 1μg/Test
抗体种类
Monoclonal
宿主来源Rat
亚细胞定位Membrane; Single-pass type I membrane protein.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.
抗原信息
基因名称
CD3E
基因ID
916
蛋白名称
T-cell surface glycoprotein CD3 epsilon chain
功能
The CD3 complex mediates signal transduction.
化学信息
分子量Theoretical: 20 kDa. Actual: 20 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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