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Anti-AGER Antibody (7O93)

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Anti-AGER Antibody (7O93)
产品编号 TMAY-03322
别名 SCARJ1, RAGE, AGER

Anti-AGER Antibody (7O93) 是一种 Rabbit 抗体,靶向 AGER。Anti-AGER Antibody (7O93) 可用于 ELISA。

Anti-AGER Antibody (7O93)
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Anti-AGER Antibody (7O93)

Rating icon 还可以
Anti-AGER Antibody (7O93)
产品编号 TMAY-03322 别名 SCARJ1, RAGE, AGER

Anti-AGER Antibody (7O93) 是一种 Rabbit 抗体,靶向 AGER。Anti-AGER Antibody (7O93) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-AGER Antibody (7O93) is a Rabbit antibody targeting AGER. Anti-AGER Antibody (7O93) can be used in ELISA.
别名SCARJ1, RAGE, AGER
Ig Type
Rabbit IgG
克隆号
7O93
交叉反应
Mouse
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse RAGE / AGER (rM RAGE / AGER; TMPY-01675; NP_031451.2; Met1-Ala342).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certain members of the S100/calgranulin family of proteins, high mobility group box 1 (HMGB1), advanced oxidation protein products, and amyloid (beta-sheet fibrils). Initial studies investigating the role of RAGE in renal dysfunction focused on diabetes, neurodegenerative disorders, and inflammatory responses. However, RAGE also has roles in the pathogenesis of renal disorders that are not associated with diabetes, such as obesity-related glomerulopathy, doxorubicin-induced nephropathy, hypertensive nephropathy, lupus nephritis, renal amyloidosis, and ischemic renal injuries. RAGE represents an important factor in innate immunity against pathogens, but it also interacts with endogenous ligands, resulting in chronic inflammation. RAGE signaling has been implicated in multiple human illnesses, including atherosclerosis, arthritis, Alzheimer's disease, atherosclerosis and aging associated diseases.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Mouse RAGE / AGER protein (TMPY-01675)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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