Anti-AGER Antibody (7O93)

Name: Anti-AGER Antibody (7O93)
Brand: TargetMol
SKU: TMAY-03322
Rating: 4.5 (1 reviews)

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产品编号 TMAY-03322

Anti-AGER Antibody (7O93) 是一种 Rabbit 抗体，靶向 AGER。Anti-AGER Antibody (7O93) 可用于 ELISA。

Anti-AGER Antibody (7O93)

还可以

产品编号 TMAY-03322

Anti-AGER Antibody (7O93) 是一种 Rabbit 抗体，靶向 AGER。Anti-AGER Antibody (7O93) 可用于 ELISA。

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产品描述	Anti-AGER Antibody (7O93) is a Rabbit antibody targeting AGER. Anti-AGER Antibody (7O93) can be used in ELISA.
Ig Type	Monoclonal Rabbit IgG
克隆号	7O93
交叉反应	Mouse
应用	ELISA
推荐剂量	ELISA: 1:5000-1:10000
抗体种类	Monoclonal
宿主来源	Rabbit
构建方式	This antibody was obtained from a rabbit immunized with purified, recombinant Mouse RAGE / AGER (rM RAGE / AGER; TMPY-01675; NP_031451.2; Met1-Ala342).
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certain members of the S100/calgranulin family of proteins, high mobility group box 1 (HMGB1), advanced oxidation protein products, and amyloid (beta-sheet fibrils). Initial studies investigating the role of RAGE in renal dysfunction focused on diabetes, neurodegenerative disorders, and inflammatory responses. However, RAGE also has roles in the pathogenesis of renal disorders that are not associated with diabetes, such as obesity-related glomerulopathy, doxorubicin-induced nephropathy, hypertensive nephropathy, lupus nephritis, renal amyloidosis, and ischemic renal injuries. RAGE represents an important factor in innate immunity against pathogens, but it also interacts with endogenous ligands, resulting in chronic inflammation. RAGE signaling has been implicated in multiple human illnesses, including atherosclerosis, arthritis, Alzheimer's disease, atherosclerosis and aging associated diseases.

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Mouse RAGE / AGER protein (TMPY-01675)
抗原种属	Mouse

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.