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Anti-EXOSC3 Polyclonal Antibody

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货号 TMAB-05743

Anti-EXOSC3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 EXOSC3。Anti-EXOSC3 Polyclonal Antibody 可用于 WB。

Anti-EXOSC3 Polyclonal Antibody

Anti-EXOSC3 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05743

Anti-EXOSC3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 EXOSC3。Anti-EXOSC3 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-EXOSC3 Polyclonal Antibody is a Rabbit antibody targeting EXOSC3. Anti-EXOSC3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Chicken,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus, nucleolus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The exosome is a multisubunit complex of 3’ to 5’ exoribonucleases. It is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich elements in their untranslated 3’ region. EXOSC3 (exosome component 3), also known as p10, CGI-102, RRP40 (Ribosomal RNA-processing protein 40), Rrp40p or hRrp40p, is a component of the exosome multienzyme ribonuclease complex. Localizing to the cytoplasm and nucleolus, EXOSC3 contains a putative S1 RNA-binding domain and is capable of binding RNA. EXOSC3 is a component of the top cap of the exosome and is essential for exosome stability. In addition, EXOSC3 is required for the processing of the 7S pre-RNA to the mature 5.8S rRNA.
抗原信息
免疫原
KLH conjugated synthetic peptide: human EXOSC3
抗原种属
Human
基因名称
EXOSC3
基因ID
蛋白名称
Exosome complex component RRP40
Uniprot ID
功能
EXOSC3 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions. It is required for the 3'processing of the 7S pre-RNA to the mature 5.8S rRNA. Has a 3'-5' exonuclease activity. [Swiss-Prot]
化学信息
分子量Theoretical: 29 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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